Synthesis and Characterizations ofN2(Aryl)-N4,N6-bis (6, 7-dichloro-1, 3-benzothiazol-2-yl)-1, 3, 5-triazine-2, 4, 6-triamines as Biological Potent Agents

Synthesis and Leishmanicidal Activity of 1-[5-(5-nitrofuran-2-yl)-1, 3, 4-thiadiazole-2-yl]-4-benzoylepiperazines

A series of (5-nitrofuran-2-yl)-1, 3, 4-thiadiazole-2-yl derivatives 6a–6e have been synthesized and screened for in vitro anti-leishmanial activity against the promastigote form of L. major. The structure of Schiff bases were confirmed by 1H NMR, IR. Screening results indicate that all of the designed and synthesized final compounds (6a-6e) significantly reduced the viability of promastigotes ...

Synthesis and Leishmanicidal Activity of 1-[5-(5-nitrofuran-2-yl)-1, 3, 4-thiadiazole-2-yl]-4-benzoylepiperazines

A series of (5-nitrofuran-2-yl)-1, 3, 4-thiadiazole-2-yl derivatives 6a–6e have been synthesized and screened for in vitro anti-leishmanial activity against the promastigote form of L. major. The structure of Schiff bases were confirmed by 1H NMR, IR. Screening results indicate that all of the designed and synthesized final compounds (6a-6e) significantly reduced the viability of promastigotes ...

2,4-Dichloro-6-(3-methyl­piperidin-1-yl)-1,3,5-triazine

In the title compound, C(9)H(12)Cl(2)N(4), the piperidine ring adopts a chair conformation. The electron delocalization of the molecule is indicated by the similar C⋯N distances within the triazine ring and by the double-bond character of the C=N triazine-piperidine connectivity. Weak intra-molecular C-H⋯N hydrogen bonds link the two rings within the mol-ecule, which exhibits a pseudo-mirror pl...

1 1 2 3 4 5 6 7 8

1 1 2 3 4 5 6

1 1 2 3 4 5 6 Complex craniofacial changes in blind cave-dwelling fish are mediated by genetically symmetric 7 and asymmetric loci 8 9 Joshua B. Gross, Amanda J. Krutzler and Brian M. Carlson 10 11 Department of Biological Sciences, University of Cincinnati, Cincinnati, Ohio 45221 12 13 14 15 16 17 18 19 20 21 22 23 Genetics: Early Online, published on February 4, 2014 as 10.1534/genetics.114.1...